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Antibiotic Resistant Bacterium Uses Sonar-like Strategy To 'See' Enemies Or Prey
For the first time, scientists have found that bacteria can use a Sonar-like system to spot other cells (either normal body cells or other bacteria) and target them for destruction. Reported in the December 24 issue of Science, this finding explains how some bacteria know when to produce a toxin that makes infection more severe. It may lead to the design of new toxin inhibitors.
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In the Science study, Gilmore and his team found that this toxin is made whenever there is another cell type in the environment near the bacterium, such as a human blood cell. They discovered how these bacteria know when other cells are present, and respond accordingly.
In the laboratory, the team found that Enterococcus releases two substances into the environment. One substance sticks to foreign cells. The second substance reports back and tells the Enterococcus to make the toxin. If no cells are in the area, the first substance sticks to the second, preventing it from reporting back to the Enterococcus, and as a result, no toxin is made. According to Gilmore, "These bacteria are actively probing their environment for enemies or food. Based on whether or not they 'see' other cells, they make the toxin appropriately."
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